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Thermal analyzers: Calorimeters
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Calorimeter with auto-sampler / DSC / differential scanning - 5 s, max. 130 µl | VP-Capillary
MicroCal VP-Capillary DSC Differential Scanning Calorimeter
Provides insights into mechanisms of unfolding and refolding.
Standard 96-well plate format for high capacity and loading ease. Up to six well plates can be stored in thermostatically controlled drawers.
Minimal assay development needed.
Study molecules in their native state without labeling. Can be used with solutions...
Provides insights into mechanisms of unfolding and refolding.
Standard 96-well plate format for high capacity and loading ease. Up to six well plates can be stored in thermostatically controlled drawers.
Minimal assay development needed.
Study molecules in their native state without labeling. Can be used with solutions...
Calorimeter with auto-sampler / DSC / differential scanning - 5 s, max. 130 µl | VP-Capillary
MicroCal VP-Capillary DSC Differential Scanning Calorimeter
Provides insights into mechanisms of unfolding and refolding.
Standard 96-well plate format for high capacity and loading ease. Up to six well plates can be stored in thermostatically controlled drawers.
Minimal assay development needed.
Study molecules in their native state without labeling. Can be used with solutions that interfere with optical methods including turbid or colored solutions or particulate suspensions.
Industry-proven stability-indicating technique.
Nonreactive Tantalum 61 cells for excellent chemical resistance and to ensure inertness when working with proteins and other biomolecules.
Direct measurement of biomolecular stability in solution.
Screen up to 50 sample/day with unattended operation
Matched capillary cells provide fast scan rates and fast temperature equilibration.
The VP-Capillary DSC System is a highly sensitive differential scanning calorimeter for characterizing the stabilty of proteins and other biomolecules. DSC directly measures the enthalpy (ΔH) and temperature (Tm) of thermally induced structural transitions in solution. This information gives valuable insights into factors that stabilize or destabilize proteins, nucleic acids, micellar complexes and many other macromolecular systems, alone or as complexes. This information can be used to predict shelf lives, develop purification strategies, and characterize and evaluate protein constructs or other biotherapeutic entities. In addition ligand affinities to a protein target in small molecule drug discovery programs can be ranked rapidly.
Provides insights into mechanisms of unfolding and refolding.
Standard 96-well plate format for high capacity and loading ease. Up to six well plates can be stored in thermostatically controlled drawers.
Minimal assay development needed.
Study molecules in their native state without labeling. Can be used with solutions that interfere with optical methods including turbid or colored solutions or particulate suspensions.
Industry-proven stability-indicating technique.
Nonreactive Tantalum 61 cells for excellent chemical resistance and to ensure inertness when working with proteins and other biomolecules.
Direct measurement of biomolecular stability in solution.
Screen up to 50 sample/day with unattended operation
Matched capillary cells provide fast scan rates and fast temperature equilibration.
The VP-Capillary DSC System is a highly sensitive differential scanning calorimeter for characterizing the stabilty of proteins and other biomolecules. DSC directly measures the enthalpy (ΔH) and temperature (Tm) of thermally induced structural transitions in solution. This information gives valuable insights into factors that stabilize or destabilize proteins, nucleic acids, micellar complexes and many other macromolecular systems, alone or as complexes. This information can be used to predict shelf lives, develop purification strategies, and characterize and evaluate protein constructs or other biotherapeutic entities. In addition ligand affinities to a protein target in small molecule drug discovery programs can be ranked rapidly.
Calorimeter DSC / differential scanning - max. 0.5 ml, 7 s | VP-DSC
Complete system, includes ThermoVac sample preparation and cleaning device. No additional accessories to purchase and no reagents or consumables are required.
Industry-proven stability-indicating technique.
Fixed-in-place cells for reproducible ultrasensitive performance with low maintenance.
Direct...
Industry-proven stability-indicating technique.
Fixed-in-place cells for reproducible ultrasensitive performance with low maintenance.
Direct...
Calorimeter DSC / differential scanning - max. 0.5 ml, 7 s | VP-DSC
Complete system, includes ThermoVac sample preparation and cleaning device. No additional accessories to purchase and no reagents or consumables are required.
Industry-proven stability-indicating technique.
Fixed-in-place cells for reproducible ultrasensitive performance with low maintenance.
Direct measurement of biomolecular stability in solution.
Nonreactive Tantalum 61 cells for excellent chemical resistance and to ensure inertness when working with proteins and other biomolecules.
Minimal assay development needed.
Study molecules in their native state without labeling. Can be used with solutions that interfere with optical methods including turbid or colored solutions or particulate suspensions.
Provides insights into mechanisms of unfolding and refolding.
The VP-DSC is a highly sensitive, easy-to-use differential scanning calorimeter for the study of samples in solution. Providing fast, accurate transition midpoint (Tm) determination, the VP-DSC has revolutionized the study of liquid biopharmaceutical formulations by reducing the time and cost of stability testing. In addition, a complete thermodynamic profile is generated to understand the factors that affect conformation and stability.
Industry-proven stability-indicating technique.
Fixed-in-place cells for reproducible ultrasensitive performance with low maintenance.
Direct measurement of biomolecular stability in solution.
Nonreactive Tantalum 61 cells for excellent chemical resistance and to ensure inertness when working with proteins and other biomolecules.
Minimal assay development needed.
Study molecules in their native state without labeling. Can be used with solutions that interfere with optical methods including turbid or colored solutions or particulate suspensions.
Provides insights into mechanisms of unfolding and refolding.
The VP-DSC is a highly sensitive, easy-to-use differential scanning calorimeter for the study of samples in solution. Providing fast, accurate transition midpoint (Tm) determination, the VP-DSC has revolutionized the study of liquid biopharmaceutical formulations by reducing the time and cost of stability testing. In addition, a complete thermodynamic profile is generated to understand the factors that affect conformation and stability.
Calorimeter ITC / titration / isothermal - 370 µl, 10 s | Auto-iTC200
MicroCal Auto-iTC200 allows direct and label-free measurement of binding affinity and thermodynamic parameters.
Exceptional data quality for sub-millimolar to picomolar binding constants.
Sensitivity to investigate any biomolecular interaction using as little as 10 µg of protein.
User-friendly experimental design wizards and automated...
Exceptional data quality for sub-millimolar to picomolar binding constants.
Sensitivity to investigate any biomolecular interaction using as little as 10 µg of protein.
User-friendly experimental design wizards and automated...
Calorimeter ITC / titration / isothermal - 370 µl, 10 s | Auto-iTC200
MicroCal Auto-iTC200 allows direct and label-free measurement of binding affinity and thermodynamic parameters.
Exceptional data quality for sub-millimolar to picomolar binding constants.
Sensitivity to investigate any biomolecular interaction using as little as 10 µg of protein.
User-friendly experimental design wizards and automated...
Exceptional data quality for sub-millimolar to picomolar binding constants.
Sensitivity to investigate any biomolecular interaction using as little as 10 µg of protein.
User-friendly experimental design wizards and automated...
Calorimeter isothermal / ITC / titration - 200 µl, 10 s | iTC200
MicroCal iTC200 allows direct and label-free measurement of binding affinity and thermodynamic parameters
User-friendly software for fast and accurate analysis
Quick to first results with no assay develoment, no labeling, and no immobilization
Exceptional data quality for sub-millimolar to picomolar binding constants
Sensitivity to investigate any biomolecular interaction...
User-friendly software for fast and accurate analysis
Quick to first results with no assay develoment, no labeling, and no immobilization
Exceptional data quality for sub-millimolar to picomolar binding constants
Sensitivity to investigate any biomolecular interaction...
Calorimeter isothermal / ITC / titration - 200 µl, 10 s | iTC200
MicroCal iTC200 allows direct and label-free measurement of binding affinity and thermodynamic parameters
User-friendly software for fast and accurate analysis
Quick to first results with no assay develoment, no labeling, and no immobilization
Exceptional data quality for sub-millimolar to picomolar binding constants
Sensitivity to investigate any biomolecular interaction...
User-friendly software for fast and accurate analysis
Quick to first results with no assay develoment, no labeling, and no immobilization
Exceptional data quality for sub-millimolar to picomolar binding constants
Sensitivity to investigate any biomolecular interaction...
Calorimeter high-sensitivity / titration / isothermal / ITC - 1 400 µl, 20 s | VP-ITC
MicroCal VP-ITC allows direct and label-free measurement of binding affinity and thermodynamic parameters.
All binding parameters (affinity, stoichiometry, enthalpy and entropy) in a single experiment.
Includes ThermoVac sample preparation and cleaning device to facilitate experiment workflow.
Directly measures millimolar to picomolar binding constants...
All binding parameters (affinity, stoichiometry, enthalpy and entropy) in a single experiment.
Includes ThermoVac sample preparation and cleaning device to facilitate experiment workflow.
Directly measures millimolar to picomolar binding constants...
Calorimeter high-sensitivity / titration / isothermal / ITC - 1 400 µl, 20 s | VP-ITC
MicroCal VP-ITC allows direct and label-free measurement of binding affinity and thermodynamic parameters.
All binding parameters (affinity, stoichiometry, enthalpy and entropy) in a single experiment.
Includes ThermoVac sample preparation and cleaning device to facilitate experiment workflow.
Directly measures millimolar to picomolar binding constants (102 to 109 M-1).
Three user selectable response times for application versatility.
Precision liquid delivery system for accurate and reproducible injections.
Non-reactive Hastelloy cells for excellent chemical resistance.
MicroCal VP-ITC system is a highly sensitive isothermal titration calorimeter designed for ease-of-use. All functions are operated through software to minimize operator involvement and facilitate fast and accurate analyses without the need for expertise in thermodynamics.
Direct and label-free measurement of binding affinity and thermodynamics are obtained with MicroCal VP-ITC. Heat released or absorbed during biochemical binding events is measured directly, giving information relative binding affinity (KD), stoichiometry (n), enthalpy (ΔH), and entropy (ΔS). This information provides valuable insights into the mechanism of binding.
MicroCal VP-ITC system is software controlled with an intelligent, easy-to-use interface. Data analysis is performed with MicroCal enabled Origin™ software, a well-established data analysis package.
All binding parameters (affinity, stoichiometry, enthalpy and entropy) in a single experiment.
Includes ThermoVac sample preparation and cleaning device to facilitate experiment workflow.
Directly measures millimolar to picomolar binding constants (102 to 109 M-1).
Three user selectable response times for application versatility.
Precision liquid delivery system for accurate and reproducible injections.
Non-reactive Hastelloy cells for excellent chemical resistance.
MicroCal VP-ITC system is a highly sensitive isothermal titration calorimeter designed for ease-of-use. All functions are operated through software to minimize operator involvement and facilitate fast and accurate analyses without the need for expertise in thermodynamics.
Direct and label-free measurement of binding affinity and thermodynamics are obtained with MicroCal VP-ITC. Heat released or absorbed during biochemical binding events is measured directly, giving information relative binding affinity (KD), stoichiometry (n), enthalpy (ΔH), and entropy (ΔS). This information provides valuable insights into the mechanism of binding.
MicroCal VP-ITC system is software controlled with an intelligent, easy-to-use interface. Data analysis is performed with MicroCal enabled Origin™ software, a well-established data analysis package.
Calorimeter differential scanning / DSC - 0.1 - 100.0 K/min | H3003
ISO 11357 requires that the oxidation induction time is determined for plastic pipes and...
Calorimeter differential scanning / DSC - 0.1 - 100.0 K/min | H3003
ISO 11357 requires that the oxidation induction time is determined for plastic pipes and conduit systems as well as fittings made from polyolefin. The test aims to establish the period in which an antioxidant remains in the test sample, preventing oxidation. The material sample is to be kept at a specified, constant temperature in flowing oxygen.
Calorimeter differential scanning / DSC - max. 7000°C
For determining OIT (Oxidation Induction Time) for polyolefin materials by means of the DSC (Differential Scanning...
Calorimeter differential scanning / DSC - max. 7000°C
For determining OIT (Oxidation Induction Time) for polyolefin materials by means of the DSC (Differential Scanning Calorimetry). The DSC analyser is an appropriate and cost-effective tool for testing and quality control laboratories. The analyser complies with standard EN ISO 728 and equivalent.
Highlights:
simple set-up
compact table model
easy maintenance
high accuracy
user-friendly
Highlights:
simple set-up
compact table model
easy maintenance
high accuracy
user-friendly